New HBM values for emerging substances, inventory of reference and HBM values in force, and working principles of the German Human Biomonitoring Commission. EVALUASI MIGRASI DI-(2-ETILHEKSIL)FTALAT DARI BOTOL POLIETILENA TEREFTALAT MENGGUNAKAN GC/MS. Effects of in utero and lactational exposure to new generation green plasticizers on adult male rats: A comparative study with di(2-ethylhexyl) phthalate. Kata kunci: Pemlastis, Ftalat, Non ftalat, Risiko kesehatanДЄlbert, O., Nardelli, T.C., Lalancette, C., Hales, B.F., Robaire, B., 2018. Di Indonesia belum ada regulasi yang mengatur pembatasan ftalat sebagai pemlastis, karena itu perlu dirancang regulasi terkait dan merekomendasikan alternatif pemlastis non ftalat yang aman bagi kesehatan. Senyawa alternatif non ftalat dianggap aman karena tidak mudah bermigrasi memajani makanan atau minuman. Nilai human biomonitoring untuk enam senyawa ftalat bervariasi pada kisaran 0,02вЂ“8 mg/kg/hari, sedangkan nilai untuk pemlastis alternatif berkisar antara 100-1000 mg/kg/hari. Bahkan salah satu senyawa ftalat yang banyak digunakan sebagai aditif pemlastis, yaitu di-(2-ethylhexyl) phtalat, dikategorikan ke dalam Golongan 2B ( probably carcinogenic). Dari hasil tinjauan literatur diperoleh informasi bahwa senyawa ftalat dikategorikan dalam senyawa toksik dan berisiko mengganggu kerja kelenjar endokrin. Setelah melalui proses pengkategorian, diperoleh 41 artikel yang digunakan sebagai referensi tinjauan. Penelusuran artikel melalui portal Google Scholar, Pubmed, dan situs resmi pemerintah/lembaga. Artikel ini bertujuan untuk melakukan tinjauan perbandingan risiko penggunaan pemlastis berbahan ftalat dan alternatif non ftalat dengan metode scoping review. Namun perlu diwaspadai risiko kesehatan dari pajanan aditif plastik berupa pemlastis yang terbuat dari senyawa ftalat. Penggunaan kemasan makanan berbahan dasar plastik menjadi pilihan karena dinilai praktis dan harganya terjangkau. Keywords: Plasticizer, Phthalate, Non-phthalate, Health risks

Therefore, it is necessary to design the relevant regulation and we recommend the safer non-pthalate alternatives for plasticizers.

There is no regulation due to phthlate restriction as plasticizer in Indonesia. These alternative phthalate compounds are relatively safer because they do not easily migrate into food or drinks. Human biomonitoring values for six phthalate compounds vary from 0.02 to 8 mg/kg/day, while alternative plasticizer compounds ranging from 100 to 1,000 mg/kg/day. One of the phthalate compounds widely used as plasticizer is di-(2-ethylhexyl) phtalat, which is categorized into Group 2B (probably carcinogenic).

The result showed that phthalates are categorized as toxic compounds which have risks to disrupt endocrine glands activities. After categorizing process, we obtained 41 articles for review refference. The articles were searched through Google Scholar, Pubmed, and official website portals. This article aims to determine the comparison of risks of using phthalate and non-phthalate as plasticizers by scoping review method. However, it is necessary to be aware of the health risks caused by exposure of phthalate plasticizer additives. The use of plastic-based food packagings has become an option considering their practicality and affordability.

Nomor lisensi cx one